Psilocybin Guide

RESEARCH-BACKED GUIDE

Wisdom in the Wild: Psilocybin Edition

Your field guide to the science of natural medicine, growing beneath your feet and beyond the trail

Wisdom in the Wild: Psilocybin Edition

Your 6-Part Field Guide to the Science of Magic Mushrooms

This FREE guide was written by a suite of PhDs dedicated to naturalistic psychedelic research. Whether you're simply curious or preparing for your own journey, this resource will help you understand psilocybin through the lens of history, pharmacology, and modern healing.

  • get the highlights from decades of data, fieldwork, and lived experience
  • distill complex information into approachable science
  • gain an evidence-based perspective on psilocybin
  • know what psilocybin is, how it works and who it has the potential to heal

With 75+ academic citations, this 6-part guide bridges emerging science with lived experience, giving you clarity, confidence, and grounded guidance in your exploration of psilocybin magic mushrooms.

"This is an absolute must-read whether you're just curious or already on your path."

— From Julie L., Psychedelic Integration Coach

Inside Our Free 6-Part Guide, You’ll Discover:

  • 🧠 How psilocybin works in the brain
    Explore its effects on serotonin receptors, neural networks, and consciousness itself
  • 🌱 Historical and cultural roots
    Learn how psilocybin has been used ceremonially and medicinally across time and cultures
  • 💊 Potential therapeutic uses
    Get a clear, evidence-based breakdown of how psilocybin is being explored for depression, anxiety, PTSD, addiction, and end-of-life care
  • ⚠️ Safety considerations and contraindications
    What to know before you begin: including interactions, side effects, and how to reduce harm
  • ⚖️ Current legal status around the world
    Understand where psilocybin is decriminalized, legal, or restricted
  • 🧭 Guidance on preparation, dosing, and integration
    Practical advice for a psilocybin experiences, with tips on mindset, setting, and navigating the journey
  • 🍄 Sourcing psilocybin safely and therapeutic access
    From types of mushrooms to psilocybin-assisted therapy, you’ll get the knowledge to make informed decisions

60+ Pages and
75+ Citations

Part 1 = History and Therapeutic Use
- What is Psilocybin?
- Use of Psilocybin Through the Ages
- Modern Medicine and Research
Part 2 = Risks, Safety and Legal Status
- Absolute Contraindications
- Contraindications and Warnings
- Challenging Experiences
- Responding to Challenges
- Interactions with Other Drugs
- Side Effects and Adverse Events
- Toxicity / Serotonin Syndrome
- Side Effects with Psilocybin
- Current Legal Status of Psilocybin
Part 3 = What to Expect
- Altered State of Consciousness
- The Intense Experience
- Onset and Peak of the Experience
- Comedown
- Navigating Challenging Experiences
- Components of Psilocybin Therapy
- Set and Setting
- Integration
Part 4 = Psychopharmacology
- Chemistry and Forms of Psilocybin
- Neurotransmitters Involved
- Pathways / Mechanisms of Action
- Tolerance to Psilocybin
Part 5 = Consumption and Dosing
- Types of Psilocybin Mushrooms
- Method of Administration
- Microdosing / Macrodosing
- Physiologic Effects of Psilocybin
- Sleep and Psilocybin
- Duration
- Effects
Part 6 = Psychedelic-Assisted Therapy
- Cost in Colorado and Oregon
- Local Laws and Regulations
- Participate in Clinical Trials
- Retreats in Legal Countries
- Quality Psilocybin Sources
- Preparation of Psilocybin

Subscribe to Get the 6-Part Guide (It’s Free!)

Instead of downloading a massive PDF, we'll email you the 60+ page guide in six focused parts to make it easy to digest. Download Part 1 of “Wisdom in the Wild: Psilocybin Edition” and take the first step into being armed with facts, not fear. 👇

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