Research Library
About Our Research Library
Scroll below to view our research library, a searchable, comprehensive collection of published, peer-reviewed psychedelic research studies.
Our collection features impactful studies on a wide range of conditions and psychedelic substances to aid you on your unique health journey.
If you’d prefer one-on-one, direct support, please reach out to our Psychedelic Info Line for free answers to all your psychedelic questions.
Our Latest Published Research
Examining differences in the effects and contexts of naturalistic psilocybin use for White participants vs. participants of Color: A longitudinal online survey study
This study used data from a large, online longitudinal study of individuals who planned to engage in naturalistic psilocybin use. We used mixed-effects models to assess whether race/ethnicity (White vs. Participant of Color) moderated outcomes related to mental health.
Shame, guilt and psychedelic experience: Results from a prospective, longitudinal survey of real-world psilocybin use
The experience of self-conscious emotions with psychedelics has been explored minimally, but further study in this area may have far-reaching implications for psychological health. The activation of shame-related experiences with psychedelics may pose a unique and context-dependent learning condition for both therapeutic and detrimental forms of shame-related memory reconsolidation.
Long-term benefits to psychological health and well-being after ceremonial use of Ayahuasca in Middle Eastern and North African immigrants and refugees
Refugees and immigrants can experience complex stressors from the process of immigration that can have lasting and severe long-term mental health consequences. Experiences after ayahuasca ingestion are shown to produce positive effects on psychological wellbeing and mental health.
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Psychedelics in the Treatment of Substance Use Disorders and Addictive Behaviors: A Scoping Review
Purpose of Review Substance use disorders (SUDs) and other addictive behaviors such as gambling disorder are globally prevalent and remain significant public health concerns. Since the 1950s, studies have examined psychedelics in the treatment of addictive behaviors with these studies demonstrating safety, feasibility, and potential therapeutic benefit. This review aims to synthesize research reports from […]
February 11, 2025
Main targets of ibogaine and noribogaine associated with its putative anti-addictive effects: A mechanistic overview
Background There is a growing interest in studying ibogaine (IBO) as a potential treatment for substance use disorders (SUDs). However, its clinical use has been hindered for mainly two reasons: First, the lack of randomized, controlled studies informing about its safety and efficacy. And second, IBO’s mechanisms of action remain obscure. It has been challenging […]
August 9, 2024
The biosynthetic pathway of the hallucinogen mescaline and its heterologous reconstruction
Abstract Mescaline, among the earliest identified natural hallucinogens, holds great potential in psychotherapy treatment. Nonetheless, despite the existence of a postulated biosynthetic pathway for more than half a century, the specific enzymes involved in this process are yet to be identified. In this study, we investigated the cactus Lophophora williamsii (Peyote), the largest known natural […]
Psilocybin‑assisted therapy and HIV‑related shame
Abstract As a proposed mediator between stigma-related stressors and negative mental health outcomes, HIV-related shame has been predictive of increased rates of substance use and difficulties adhering to antiretroviral treatment among people with HIV. These downstream manifestations have ultimately impeded progress toward national goals to End the HIV Epidemic, in part due to limited success […]
August 8, 2024
Psychedelic‑assisted psychotherapy: where is the psychotherapy research?
Rationale Psychedelic-assisted psychotherapy (PAP) has emerged as a potential treatment for a variety of mental health conditions, including substance use disorders and depression. Current models of PAP emphasize the importance of psychotherapeutic support before, during, and after ingestion of a psychedelic to maximize safety and clinical beneft. Despite this ubiquitous assumption, there has been surprisingly […]
July 18, 2024
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