Should I be on a specific diet when using psilocybin?

Regarding diet, nausea is a common side effect of psilocybin ingestion. Mushrooms are largely made up of chitin, an indigestible polysaccharide that can cause gastrointestinal distress. Chitin-glucan is an insoluble dietary fiber extracted from the cell wall of the fungi with many potential health benefits (Shahidi and Abuzaytoun, 2005). Although repeated-ingestion of chitin suggests potential positive effects on the complex microbial community in the human body (Marzorati et al., 2017), it can also trigger inflammation and immune responses (Komi et al., 2018). leading to gastrointestinal issues and nausea. Accumulating research on ginger (Zingiber officinale) shows that ginger can alleviate clinical nausea of diverse causes (Ernst and Pittler, 2000). Ginger can be ingested in many ways, such as fresh, dried, pickled, crystalized, candied, powder, or ginger root tea, among others.

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