Validation of the revised Mystical Experience Questionnaire in experimental sessions with psilocybin

Abstract

The 30-item revised Mystical Experience Questionnaire (MEQ30) was previously developed within an online survey of mystical-type experiences occasioned by psilocybin-containing mushrooms. The rated experiences occurred on average eight years before completion of the questionnaire. The current paper validates the MEQ30 using data from experimental studies with controlled doses of psilocybin. Data were pooled and analyzed from five laboratory experiments in which participants (n=184) received a moderate to high oral dose of psilocybin (at least 20 mg/70 kg). Results of confirmatory factor analysis demonstrate the reliability and internal validity of the MEQ30. Structural equation models demonstrate the external and convergent validity of the MEQ30 by showing that latent variable scores on the MEQ30 positively predict persisting change in attitudes, behavior, and well-being attributed to experiences with psilocybin while controlling for the contribution of the participant-rated intensity of drug effects. These findings support the use of the MEQ30 as an efficient measure of individual mystical experiences. A method to score a “complete mystical experience” that was used in previous versions of the mystical experience questionnaire is validated in the MEQ30, and a stand-alone version of the MEQ30 is provided for use in future research.

Stay Updated On Psychedelic News

Join our newsletter to receive updates about the latest psychedelic news, hear about our ground-breaking research, and learn what we think about the latest trends shaping the future of psychedelics.

Planning Your Psychedelic Trip?
Our Info Line Can Help.

We provide 100% free, 1:1 guidance for anyone preparing for a psychedelic experience. Learn more about our evidence-based approach or book a call today.

Learn MoreBook a Call

About:

Conditions:

Research Keywords:

Subscribe for Access and Updates

Join our email list and get immediate access to part one of our psilocybin guide. You’ll also get the latest in how we’re bridging the gap between science and soul: psychedelic research updates, real-world findings, community-driven education, personal stories and expert insights on natural medicine.

Get Free Access To Our 6-Part Psilocybin Guide

Unlimited Sciences

Advancing Real-World Psychedelic Research and Science-Backed Education

Unlimited Sciences is provided with a nonprofit status by fiscal sponsorship through Realm of Caring Foundation.

Federal EIN: 46-3371348.

© 2025 Unlimited Sciences. All Rights Reserved.

Designed by Gloss

Unlimited Sciences
Privacy Overview

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.